(1) sebenzisa "indlela yobunjiniyela bevalue" ukuthenga okokusebenza, izinqubo ezithile zimi kanje. Izidingo ezicacile, nquma ukukhetha nokuthenga imishini - imininingwane yebhizinisi eliqondiwe (ulwazi luhlanganisa: inqubomgomo yokusebenza, umgomo wokuphatha, isikali sombuso wokukhiqiza nokuphatha, njll.) - umkhiqizo ohlosiwe wahlaziywa, ukuhlaziywa kwemikhiqizo ehlosiwe yenhlawulo, okungukuthi ukuhlukaniswa komsebenzi, umsebenzi othize nocacile, khona-ke, ukuhlaziywa komsebenzi wemishini kanye nezinga elihambisanayo lesidingo sangempela, kucatshangelwa ukusebenza kwemishini, uhlelo lokuxoxisana olusebenzayo kanye nokuhlelwa kweqembu okusebenzayo - ngokucutshungulwa kochwepheshe beqembu kanye nokuhlelwa kwengxoxo) izinzuzo kanye nokubi okokusebenza ukwenza ukuhlaziywa kwezindleko bese, bese, ukuhlanganisa into eyinhloko, nokuhlunga), ukunquma okuhlosiwe kokukhetha nokuthenga.

(2) ukufakwa nokwamukelwa kwemishini yokwenza imithi. Ngokuqinile ngokuhambisana nezidingo ze-GMP kanye nezinqubo zokusebenza ezihlobene zokufakwa nokwamukelwa kwemishini yezemithi. Abahlanganyeli bahlanganisa: ukukhiqiza, ubunjiniyela, amandla, i-QA kanye nochwepheshe bangaphandle. Inqubo ethize yilena: ukuqinisekiswa kokufakwa, ukuqinisekiswa kokusebenza. I-QA inesibopho sokuhlola nokuqinisekisa iphrojekthi ye-GMP, ukuhlola nokuqinisekisa.

(3) ukwakhiwa kolwazi. Ngokuya ngebhukwana lobuchwepheshe lemishini kanye ne-GMP, thintana nochwepheshe abafanelekile, hlanganisa ithebula lokugcinwa kwemishini kanye nebhukwana lobuchwepheshe, futhi urekhode ngokuningiliziwe idatha yokulungisa yangaphambilini, izindlela zokunakekela kanye nemiphumela yokulungisa, ukuze kugqugquzelwe ukwaziswa kanye nokumiswa kokuphathwa nokugcinwa kwempahla yemithi.

(4) ukusebenzisa uhlelo “lwezikhathi ezimbili”. Njengoba ukuphathwa kwemishini yemithi kubonakala ngobungcweti obuqinile, izinkinga eziyinkimbinkimbi kanye nohlu olubanzi lwemikhakha, kanye nokuzuma nokufihla ukwehluleka kwemishini, kudinga ukuba sisungule ukusebenza okusheshayo nangempumelelo, indlela yokuphendula kanye nokusingatha ukwehluleka ngesikhathi. I-Shift briefing (ibhekisela ekusetshenzisweni kwemizuzu eyi-10 ngaphambi kokuya emsebenzini nsuku zonke, ukufingqa nokuxoxa ngosuku olu-1 ngaphambi komsebenzi nohlelo lomsebenzi walolu suku) kanye nomhlangano wamasonto onke womnyango (ukuhlola, ukubukeza ukusebenza kuleli sonto, kuleli sonto ukuze kuxoxwe ngezinkinga eziyinhloko, ukuxoxisana ngesixazululo, nokumisa uhlelo lomsebenzi ngesonto elizayo), olungathuthukisa ngempumelelo ukulinganiswa komsebenzi okufihliwe, kubaluleke kakhulu ukunciphisa ingozi yokuphepha.